With the development of research on the impact of immunity and inflammation on cancer,the performance of humanized mice has attracted tremendous attention in clinical oncology research. Generally,humanized mice have been divided into two categories, namely,immunocompromised and immunocompetent mouse models.
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The COVID-19 pandemic caused by the novel coronavirus (SARS-CoV-2) infection has resulted in more than 330 million infections worldwide. The spike (S) protein of SARS-CoV-2 is responsible for host receptor recognition and the fusion of viral and cellular membranes, resulting in viral infection of host cells.
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